Can nanoparticles and other pollutants have connections with Alzheimer's?

Can nanoparticles and other pollutants have connections with Alzheimer's?

"Purdue researchers have uncovered how fat-laden immune cells in the brain fuel Alzheimer’s. Credit: Shutterstock" (ScitechDaily, New Research Overturns Decades of Thinking on Fat’s Role in Alzheimer’s)

"For many years, scientists believed that fat in the brain had little connection to neurodegenerative diseases. Purdue University researchers are now challenging that view." (ScitechDaily, New Research Overturns Decades of Thinking on Fat’s Role in Alzheimer’s)

"Their study, published in Immunity, demonstrates that an accumulation of fat in microglia, the brain’s immune cells, weakens their disease-fighting capacity. The discovery points toward new therapeutic strategies in lipid biology that could support microglial activity and improve neuronal health in conditions such as Alzheimer’s. The work was led by Gaurav Chopra, the James Tarpo Jr. and Margaret Tarpo Professor of Chemistry and (by courtesy) of Computer Science at Purdue." (ScitechDaily, New Research Overturns Decades of Thinking on Fat’s Role in Alzheimer’s)

Researchers noticed. There is a connection between Alzheimer’s and nanoplastics. There is a possibility that pollutions simply block small blood vessels in the brain. And that causes a situation where dirt starts to accumulate in those blood vessels. That thing can decrease and block nutrients. From cells that those small capillaries should feed. 

So could the nanoparticles cause Alzhemers's in the same way as smoking cigarettes causes coronary artery disease? In those cases, nanoparticles simply block the coronary arteries. That causes. The heart and its muscles don’t get enough nutrients and oxygen. This can explain why alcoholism also causes those diseases. Alcohol dissolves fat that will suck in blood vessels. And that can cause heart attacks and also things like Alzheimer’s. Alcohol also dissolves proteins from the myelin cells’ shells. And that lets dangerous plaque move between those cells. That plague can jam the myelin cell’s ability to take nutrients by blocking its ion pumps. 

If the blood vessels are jammed, that means the cells that the blocked blood vessel feeds get without nutrients. When we think about Alzheimer’s, there is a possibility that the microplastics can be stuck in the small blood vessels in the brain. Those microplastics cause a point to form in the blood vessels. That starts to accumulate impurities at that point. That means Alzheimer’s can be similar to coronary artery disease. Some kind of dirt in the blood vessels blocks them. And if that happens in the blood vessels. That feeds brain cells. That decreases those cells’ ability to get nutrients and oxygen. This decreases their ability to accomplish their mission. 

"A University of Rhode Island study suggests micro- and nanoplastics can accumulate in the brain, potentially accelerating Alzheimer’s symptoms in genetically at-risk individuals. Credit: Stock". "(ScitechDaily, Microplastics May Trigger Alzheimer’s-Like Brain Damage)

The reason why nanoparticles can have a connection with Alzheimer’s is simple. Those particles can block the smallest blood vessels in the brain. When blood flow in those small blood vessels slows or becomes difficult, this can cause an effect. Immune cells cannot reach all areas of the brain. And that causes the accumulation of the plague. The model goes like this. In normal brains, blood vessels are large enough. The immune cells reach all brain areas. Their mission is to remove zombie cells and other things. And if immune cells have no access to all brain areas, that forms blocks and plaques in those areas. 

Like metabolic waste that cells form in metabolism. Even if neurons are well protected against infections. The myelin cells that feed neurons are where Alzheimer’s forms. Things like sniffing glues cause situations where there are holes in the myelin structure. And then the plague can slip through this protective muzzle.  Some of those holes can also form, if the myelin cell turns overage. 

Another case is that the small particles can cause Alzheimer’s. Because those particles don’t allow the immune cells to clean the farthest points in the smallest blood vessels. If things like fullerene slip into the blood vessels, those things form bubbles in the blood plasma. And those ball-shaped carbon molecules can also slip into the cells, and if there is some kind of acoustic effect that puts the fullerene into oscillation, that oscillation forms millions of bubbles in the blood vessels. 

Those bubbles can jam the blood flow. Or they can destroy the immune system’s cells. They can affect another cell type’s internal structure. If small particles. Slipping into the myelin cells, it can cause a situation where the cell cannot get enough nutrients.  In the same way. If the cell that transports nutrients is filled with bubbles, that means it cannot carry enough nutrients to the cells. 

Bubbles are always dangerous, because they can decay. When the oscillating membrane pulls the bubble larger, that causes an effect where a low-pressure area forms around that bubble. The low-pressure area causes a situation where a small part of the fluid boils. And that effect forms more bubbles. When there are enough bubbles in some blood vessels, they simply block those vessels. 

https://scitechdaily.com/microplastics-may-trigger-alzheimers-like-brain-damage/

https://scitechdaily.com/new-research-overturns-decades-of-thinking-on-fats-role-in-alzheimers/